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产品目录

ASC/TMS1/PYCARD抗体图片
产品货号:
Z11225
中文名称:
ASC/TMS1/PYCARD抗体
英文名称:
Anti-ASC/TMS1/PYCARD Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-ASC/TMS1/PYCARD Antibody
指标别名PYCARD;ASC;CARD5;TMS1;Apoptosis-associated speck-like protein containing a CARD;hASC;Caspase recruitment domain-containing protein 5;PYD and CARD domain-containing protein;Target of methylation-induced silencing 1
克隆性Polyclonal
检验物种human
应用范围WB,IHC,IF,ICC/IF,FCM(Intracellular),Direct ELISA
基因名称PYCARD
抗体来源Rabbit
抗体类型IgG
免疫原E.coli-derived human ASC/TMS1/PYCARD recombinant protein (Position:M1-S195).
实际分子量24KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料PYCARD,often referred to as ASC (Apoptosis-associated speck-like protein containing a CARD),is a protein that in humans is encoded by the PYCARD gene.This gene encodes an adaptor protein that is composed of two protein-protein interaction domains:a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD).The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase.In normal cells,this protein is localized to the cytoplasm;however,in cells undergoing apoptosis,it forms ball-like aggregates near the nuclear periphery.Two transcript variants encoding different isoforms have been found for this gene.
Uniprot IDQ9ULZ3
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC.
基因名全称PYD and CARD domain containing
蛋白名全称Apoptosis-associated speck-like protein containing a CARD
推荐稀释比
Western blot (WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
Immunofluorescence (IF) 1:50~400
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400
Flow Cytometry(Intracellular) 1~3μg/1×106 cells
Direct ELISA 1:100~1000
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:ASC/TMS1/PYCARD抗体ASC抗体TMS1抗体PYCARD多抗Anti-ASC/TMS1/PYCARD Antibody
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